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The The Cancer Genome Atlas (TCGA) Head-Neck Phenotype Research Group is part of the Cancer Imaging Program TCGA Radiology Initiative focused on analyzing images from the TCGA-Head and Neck Squamous Cell Carcinoma (HNSC) collection. Multiple modalities of images which correlate to the head-neck tissue data in the TCGA Data Portal are being gathered for submission to The Cancer Imaging Archive (TCIA).

According to the TCGA page on HNSC, researchers hope to make the following types of discoveries:

  • Determine whether patterns of genomic changes are different between tumors that metastasize to other regions of the body and tumors that remain in the region of origin.
  • Identify genomic differences that distinguish tumors across age and smoking history.
  • Identify genomic differences that are associated with viral infection.

Research and Publications

Per TCGA and TCIA Guidelines, formal permission requests are still required to submit publications using TCGA-HNSC data. Please see the following links for more information about the freedom-to-publish criteria for these data sets:

Data Source


TCGA Data Portal Publication Guidelines

No restrictions; all data available without limitations.

TCIA Data Usage Policies and Restrictions

Projects have not reached 100 imaging cases; Please check with prior to any publication.

Please contact us at if you have any questions about these policies.

TCGA Head-Neck Marker Paper and Image Source Sites (ISS)

Imaging Source Site (ISS) Groups will be populated and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, ISS groups are given the opportunity to publish a marker paper for a given cancer type per the guidelines in the table above. This opportunity will generate increased participation in building these multi-institutional data sets as they become an open community resource. Current TCGA-HNSC source sites include:

  • University of Pittsburgh / UPMC

This group has not yet been established. We will provide a point of contact for the group from the ISS site(s) as soon as possible to address scientific questions or requests to collaborate with their group.


The following links contain publications from the main TCGA project as well as their posted publication guidelines:

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