Nasopharyngeal carcinoma has a higher incidence in China, and it is more common in the southeast coast. MRI and PET-CT are indispensable imaging modalities that can more accurately assess the stage of tumor and guide the treatment planning and evaluation of normal tissue response. The Department of radiation oncology in our hospital has performed the treatment of nasopharyngeal cancer for many years. Has a wealth of clinical experience and a large number of nasopharyngeal carcinoma patients. Inclusion criteria: 1. All patients are pathologically confirmed nasopharyngeal carcinoma, 2. KPS score is larger than 60 and no other serious cardiovascular disease that could affect the course of treatment. Exclusion criteria: The expected survival time is less than 1 month, and the general condition is poor and radiotherapy cannot be completed. Take a CT, MRI and upload the data in imaging archive at the time before radiotherapy, during 15-20 fraction, 1 month after radiotherapy, 3 months after radiotherapy, 6 months after radiotherapy, 9 months after radiotherapy, 1 year after radiotherapy.
Nasopharyngeal carcinoma has a higher incidence rate in Taizhou city. Taizhou Hospital is the largest general hospital in the local region. It has the largest nasopharyngeal carcinoma resources and can represent the highest level of nasopharyngeal diagnosis and treatment in Taizhou. By analyzing our imaging data, we try to to investigate predictive and prognostic radiomic parameters of treatment and survival outcomes for IMRT treated NPC. Also we are going to correlate the difference in radiomic features between MRI and PET-CT scan in predicting treatment and survival outcomes.
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Jian Z, Meng Y, Yang H, Kong FS. Nasopharyngeal Carcinoma Radiomics Study Database. 2018.
Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. (paper)
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