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  • The Cancer Genome Atlas Lung Adenocarcinoma Collection (TCGA-LUAD)

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Summary

The TCGA-LUAD data collection is part of a larger effort to enhance the The Cancer Genome Atlas (TCGA) data set with characterized radiological images.  The Cancer Imaging Program (CIP) with the cooperation of several of the TCGA tissue-contributing institutions has archived a large portion of the radiological images of the genetically-analyzed Lung adenocarcinoma (LUAD) cases.

Clinical, genetic, and pathology data resides in the TCGA data portal while the radiological data is stored on The Cancer Imaging Archive (TCIA).   The data utilizes the same TCGA patient identifiers in both repositories, allowing researchers to explore the correlations between tissue genotype and radiological phenotype. This Collection within TCIA is related to the LUAD disease type within TCGA.

We would like to acknowledge the individuals and institutions that have provided data for this collection:

  • Washington University in St. Louis, St. Louis, MO - Special thanks to Mark Watson, MD, PhD from the Tissue Procurement and Multiplexed Gene Analysis Laboratories, Washington University School of Medicine.

Metadata

The TCGA data portal has extensive clinical and genomic data which can be matched to the patient identifiers of the images here in TCIA.  Here are just a sample of some of the clinical data types available:

bcr_patient_barcode,age_at_initial_pathologic_diagnosis,days_to_birth,days_to_death,days_to_form_completion,days_to_initial_pathologic_diagnosis,
days_to_last_followup,days_to_last_known_alive,distant_metastasis_pathologic_spread,drugs,eastern_cancer_oncology_group,erythrocyte_sedimentation_rate_result,
gender,hemoglobin_result,histological_type,informed_consent_verified,karnofsky_performance_score,lactate_dehydrogenase_result,laterality,
lymphnode_pathologic_spread,lymphnodes_examined_prior_presentation,number_of_lymphnodes_examined,number_of_lymphnodes_positive,performance_status_scale_timing,
person_neoplasm_cancer_status,platelet_qualitative_result,pretreatment_history,primary_tumor_pathologic_spread,prior_diagnosis,radiations,serum_calcium_result,
tumor_grade,tumor_stage,tumor_tissue_site,vital_status,white_cell_count_result,year_of_initial_pathologic_diagnosis

Data Access

Collection Statistics

(updated 10/24/2012)

Modalities

CT, PT

Number of Patients

38

Number of Studies

90

Number of Series

360

Number of Images

16,408

You can view and download these images on the Cancer Imaging Archive by selecting the TCGA-LUAD collection. If you are unsure how to download this Collection view our quick guide on Searching by Collection or you can refer to our The Cancer Imaging Archive User's Guide for more detailed instructions on using the site.

CIP TCGA Radiology Initiative

The Cancer Imaging Program is supporting multiple projects within the academic community to encourage cross disciplinary research which utilizes the data provided in these resources.  Much more can be learned about this effort on the TCGA Lung Phenotype Research Group page.

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