Study ID and TP | Reason for rejection for volumetric SER analysis (level 2a) |
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1007 T4 * | No fatSat; Different protocol from T1 | 1035 T4 * | Only 1 post scan then acq. parameters changed | 1045 T1 | Alternating laterality acquisitions, 2 minute time gap | 1047 T1 * | Image position changed during DCE | 1053 T2 * | Alternating laterality acquisitions, bad pre- acquisition | 1053 T4 * | Alternating laterality acquisitions | 1055 T1 * | Alternating laterality acquisitions, 4 minute time gap | 1086 T1 * | Alternating laterality acquisitions, time gap, different protocol from T4 | 1091 T1 * | Changing acq. parameters during DCE | 1095 T2 * | Only 1 post scan then acq. parameters changed | 1173 T3 * | Off protocol timing | 1206 T1 | Bad DCE timing, 20 minute delay | 1206 T2 | Bad DCE timing, 1'29" acquisition time | 1224 T3 * | Scan position changed during DCE | 1230 T3 * | Scan position changed during DCE | #128 T1, T2 | 2 studies for ineligible patient: ACRIN ID 128 (no I-SPY ID) | - Subjects that were included in the primary aim analysis (Level 3)
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Level 3: Subset of Level 2b used in primary aim analysis, reported in Hylton et al. (Radiology, 2016) *This data set is comprised of the patient studies analyzed for RFS outcome and reported in the 2015 Radiology paper on ACRIN 6657 survival results (Hylton et al, Radiology *). Table 5 shows the 45 patients excluded from the level 2a cohort for this analysis. Please see the publication for specific information on exclusions of patients from this group. Level 3 image data set consists of 586 MRI studies on 162 subjects in the UCSF image database. This is also the study cohort used as the Test Phase data in the QIN BMMR Challenge.
Table 5. 45 subjects excluded from Level 2b set |
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ID 1027 ID 1040 ID 1045 ID 1046 ID 1048 ID 1054 ID 1063 ID 1067 | ID 1079 ID 1084 ID 1103 ID 1110 ID 1120 ID 1137 ID 1139 ID 1152 | ID 1157 ID 1159 ID 1160 ID 1167 ID 1171 ID 1176 ID 1177 ID 1180 | ID 1182 ID 1185 ID 1187 ID 1189 ID 1192 ID 1194 ID 1203 ID 1206 | ID 1210 ID 1212 ID 1214 ID 1215 ID 1219 ID 1221 ID 1222 ID 1228 | ID 1234 ID 1235 ID 1237 ID 1238
ineligible: Case #: 128 |
- Hylton, N. M., Gatsonis, C. A., Rosen, M. A., Lehman, C. D., Newitt, D. C., Partridge, S. C., Bernreuter, W. K., Pisano, E. D., Morris, E. A., Weatherall, P. T., Polin, S. M., Newstead, G. M., Marques, H. S., Esserman, L. J., & Schnall, M. D. (2016). Neoadjuvant Chemotherapy for Breast Cancer: Functional Tumor Volume by MR Imaging Predicts Recurrence-free Survival—Results from the ACRIN 6657/CALGB 150007 I-SPY 1 TRIAL. https://doi.org/10.1148/radiol.2015150013 PMC4819899
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| David Newitt, Nola Hylton, on behalf of the I-SPY 1 Network and ACRIN 6657 Trial Team. (2016). Multi-center breast DCE-MRI data and segmentations from patients in the I-SPY 1/ACRIN 6657 trials. The Cancer Imaging Archive. https://doi.org/10.7937/K9/TCIA.2016.HdHpgJLK |
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title | Publication Citation |
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| Hylton, N. M., Gatsonis, C. A., Rosen, M. A., Lehman, C. D., Newitt, D. C., Partridge, S. C., Bernreuter, W. K., Pisano, E. D., Morris, E. A., Weatherall, P. T., Polin, S. M., Newstead, G. M., Marques, H. S., Esserman, L. J., & Schnall, M. D. (2016). Neoadjuvant Chemotherapy for Breast Cancer: Functional Tumor Volume by MR Imaging Predicts Recurrence-free Survival—Results from the ACRIN 6657/CALGB 150007 I-SPY 1 TRIAL. In Radiology (Vol. 279, Issue 1, pp. 44–55). Radiological Society of North America (RSNA). https://doi.org/10.1148/radiol.2015150013 |
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| Clark, K., Vendt, B., Smith, K., Freymann, J., Kirby, J., Koppel, P., Moore, S., Phillips, S., Maffitt, D., Pringle, M., Tarbox, L., & Prior, F. (2013). The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository. In Journal of Digital Imaging (Vol. 26, Issue 6, pp. 1045–1057). Springer Science and Business Media LLC. https://doi.org/10.1007/s10278-013-9622-7 PMCID: PMC3824915 |
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