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Summary

The TCGA-KIRC data collection is part of a larger effort to enhance the The Cancer Genome Atlas (TCGA) data set with characterized radiological images.  The Cancer Imaging Program (CIP) with the cooperation of several of the TCGA tissue-contributing institutions has archived a large portion of the radiological images of the genetically-analyzed Kidney renal clear cell carcinoma (KIRC) cases.Clinical, genetic, and pathology data resides in the TCGA data portal while the radiological data is stored on The Cancer Imaging Archive (TCIA).   The data utilizes the same TCGA patient identifiers in both repositories, allowing researchers to explore the correlations between tissue genotype and radiological phenotype. This Collection within TCIA is related to the KIRC disease type within TCGA.

We would like to acknowledge the individuals and institutions that have provided data for this collection:

  • Memorial Sloan-Kettering Cancer Center, New York, NY - Special thanks to Oguz Akin, MD and Pierre Elnajjar.
  • University of Pittsburgh/UPMC, Pittsburgh, PA - Special thanks to Matthew Heller, MD and Rose Jarosz.
  • Mayo Clinic, Rochester, MN - Special thanks to Bradley J. Erickson, MD, PhD from the Department of Radiology, Mayo Medical School.

Note: Per TCGA Guidelines, formal permission requests are still required for publications using TCGA-KIRC data. More info about TCGA Publication Policies can be found on the Data Usage Policies and Restrictions page.

CIP TCGA Radiology Initiative

The Cancer Imaging Program is supporting multiple projects within the academic community to encourage cross disciplinary research which utilizes the data provided in these resources.  Much more can be learned about this effort on the TCGA-KIRC Phenotype Research Group page.

Data Access

Imaging Data

You can view and download these images on The Cancer Imaging Archive by logging in to TCIA and selecting the TCGA-KIRC collection. A full listing of the available imaging studies/series for each patient can be found in this spreadsheet:TCGA-KIRC_series_descriptions.csv

Collection Statistics

(updated 11/15/2013)

Modalities

CT, MR

Number of Patients

162

Number of Studies

291

Number of Series

1657

Number of Images

115871

If you are unsure how to download this Collection please view our quick guide on Searching by Collection or refer to our The Cancer Imaging Archive User's Guide for more detailed instructions on using the site.

Metadata

The TCGA data portal has extensive clinical and genomic data which can be matched to the patient identifiers of the images here in TCIA.  Here are just a sample of some of the clinical data types available:

 

bcr_patient_barcode,age_at_initial_pathologic_diagnosis,days_to_birth,days_to_death,days_to_form_completion,days_to_initial_pathologic_diagnosis,
days_to_last_followup,days_to_last_known_alive,distant_metastasis_pathologic_spread,drugs,eastern_cancer_oncology_group,erythrocyte_sedimentation_rate_result,
gender,hemoglobin_result,histological_type,informed_consent_verified,karnofsky_performance_score,lactate_dehydrogenase_result,laterality,
lymphnode_pathologic_spread,lymphnodes_examined_prior_presentation,number_of_lymphnodes_examined,number_of_lymphnodes_positive,performance_status_scale_timing,
person_neoplasm_cancer_status,platelet_qualitative_result,pretreatment_history,primary_tumor_pathologic_spread,prior_diagnosis,radiations,serum_calcium_result,
tumor_grade,tumor_stage,tumor_tissue_site,vital_status,white_cell_count_result,year_of_initial_pathologic_diagnosis

Verbose explanations of the clinical data can be found on the Biospecimen Core Resource Clinical Data Forms linked below:

 

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