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Summary

The Cancer Genome Atlas-Prostate Adenocarcinoma (TCGA-PRAD) data collection is part of a larger effort to enhance the TCGA data set with characterized radiological images. The Cancer Imaging Program (CIP) with the cooperation of several of the TCGA tissue-contributing institutions has archived a large portion of the radiological images of the genetically-analyzed PRAD cases.Clinical, genetic, and pathological data resides in the TCGA data portal, while the radiological data is stored on The Cancer Imaging Archive (TCIA). The data utilizes the same TCGA patient identifiers in both repositories, allowing researchers to explore the correlations between tissue genotype and radiological phenotype. This collection within TCIA is related to the PRAD disease type within TCGA.

CIP TCGA Radiology Initiative

The CIP is supporting multiple projects within the academic community to encourage cross disciplinary research, which utilizes the data provided in these resources. More can be learned about this effort on the TCGA-PRAD Phenotype Research Group page.

Acknowledgements

We would like to acknowledge the individuals and institutions that have provided data for this collection:

  • University of Pittsburgh/UPMC, Pittsburgh, PA - Special thanks to Margarita L Zuley MD, and Rose Jarosz.
  • Washington University, Saint Louis, MO - Special thanks to Bettina F. Drake, PhD,Danielle Rancilio, and Aleksandra Klim, Department of Surgery.

 

 

Data Access

Choosing the Download option will provide you with a file to launch the TCIA Download Manager to download the entire collection. If you want to browse or filter the data to select only specific scans/studies please use the Search By Collection option.

Data TypeDownload all or Query/Filter
Images (DICOM, 1.75GB) 
Clinical Data (TXT)
Genomics (web)

Click the Versions tab for more info about data releases.

Detailed Description

Image Statistics

 Updated 2015/06/30

Modalities

CT, PT, MR

Number of Patients

7

Number of Studies

13

Number of Series

67

Number of Images

5,225

Images Size (GB)1.75

TCGA Data Portal - Clinical and Genomic Data

The TCGA data portal has extensive clinical and genomic data, which can be matched to the patient identifiers of the images here in TCIA.  Below is a snapshot of clinical data extracted on 11/4/2014.

Explanations of the clinical data can be found on the Biospecimen Core Resource Clinical Data Forms linked below:

A Note about TCIA and TCGA Subject Identifiers and Dates

Subject Identifiers: a subject with radiology images stored in TCIA is identified with a Patient ID that is identical to the Patient ID of the same subject with demographic, clinical, pathological, and/or genomic data stored in TCGA. For each TCGA case, the baseline TCGA imaging studies found on TCIA are pre-surgical. 

Dates: TCIA and TCGA handle dates differently, and there are no immediate plans to reconcile:

  • TCIA Dates: dates (be they birth dates, imaging study dates, etc.) in the Digital Imaging and Communications in Medicine (DICOM) headers of TCIA radiology images have been offset by a random number of days. The offset is a number of days between 3 and 10 years prior to the real date that is consistent for each TCIA image-submitting site and collection, but that varies among sites and among collections from the same site. Thus, the number of days between a subject’s longitudinal imaging studies are accurately preserved when more than one study has been archived while still meeting HIPAA requirements.
  • TCGA Dates: the patient demographic and clinical event dates are all the number of days from the index date, which is the actual date of pathologic diagnosis. So all the dates in the data are relative negative or positive integers, except for the “days_to_pathologic_diagnosis” value, which is 0 – the index date. The years of birth and diagnosis are maintained in the distributed clinical data file. The NCI retains a copy of the data with complete dates, but those data are not made available.With regard to other TCGA dates, if a date comes from a HIPAA “covered entity’s” medical record, it is turned into the relative day count from the index date. Dates like the date TCGA received the specimen or when the TCGA case report form was filled out are not such covered dates, and they will appear as real dates (month, day, and year).

 

Citations & Data Usage Policy 

TCGA collections have special publication embargoes which must be followed in addition to our normal data usage policies. See the TCGA section within TCIA's Data Usage Policies and Restrictions for additional details. After the publication embargo period ends these collections are freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License. Questions may be directed to help@cancerimagingarchive.net. Please be sure to acknowledge both this data set and TCIA in publications by including the following citations in your work:

TCGA-BLCA Citation

DOI coming soon

TCIA Citation

Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. (paper)

Other Publications Using This Data

TCIA maintains a list of publications which leverage our data. At this time we are not aware of any manuscripts based on this data. If you have a manuscript you'd like to add please contact the TCIA Helpdesk.

 

Version 1 (Current): Updated 2015/06/30

Data TypeDownload all or Query/Filter
Images (DICOM, 1.75GB) 
Clinical Data (TXT)
Genomics (web)

 

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