Summary
Phase II Study of 3'-Deoxy-3'-18F Fluorothymidine (FLT) in Invasive Breast Cancer Main Objective: To evaluate the relationship between [18F]FLT uptake parameters and pathologic complete response to neoadjuvant therapy of the primary tumor in patients with locally advanced breast cancer. Design Summary: Patients with locally advanced breast cancer who are candidates for primary systemic (neoadjuvant) therapy and for whom subsequent definitiate surgery is planned (according to current clinical guidelines) may be eligible for this trial. Participants will be required to have three 2-day imaging sessions using FLT and FDG-PET/CT to evaluate therapy response (baseline, mid-treatment, and just prior to surgical resection of residual tumor).
ACKNOWLEDGEMENT: Thanks to Laura Coombs and Brian Bialecki
Data Access
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Detailed Description
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Metadata
Much more information about this data set can be found https://www.acrin.org/6688_protocol.aspx
Citations & Data Usage Policy
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Please be sure to include the following citations in your work if you use this data set:
Data Citation
(authors list coming soon). (2017). Data from ACRIN-FLT-Breast. The Cancer Imaging Archive. http://doi.org//
TCIA Citation
Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. (paper)
Other Publications Using This Data
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