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Summary

Phase II Study of 3'-Deoxy-3'-18F Fluorothymidine (FLT) in Invasive Breast Cancer

Main Objective: To evaluate the relationship between [18F]FLT uptake parameters and pathologic complete response to neoadjuvant therapy of the primary tumor in patients with locally advanced breast cancer.

Design Summary: Patients with locally advanced breast cancer who are candidates for primary systemic (neoadjuvant) therapy and for whom subsequent definitiate surgery is planned (according to current clinical guidelines) may be eligible for this trial. Participants will be required to have three 2-day imaging sessions using FLT and FDG-PET/CT to evaluate therapy response (baseline, mid-treatment, and just prior to surgical resection of residual tumor).

Much more information about this data set can be found https://www.acrin.org/6688_protocol.aspx and for ACRIN in general here. https://www.acrin.org/


ACKNOWLEDGEMENT: Thanks to Laura Coombs and Brian Bialecki

 

Data Access

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Detailed Description

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Metadata

Much more information about this data set can be found https://www.acrin.org/6688_protocol.aspx

Citations & Data Usage Policy 

This collection is freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License.  See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to help@cancerimagingarchive.net.

Please be sure to include the following citations in your work if you use this data set:

Data Citation

(authors list coming soon). (2017). Data from ACRIN-FLT-Breast. The Cancer Imaging Archive. http://doi.org//

TCIA Citation

Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. (paper)

Other Publications Using This Data

TCIA maintains a list of publications which leverage our data. At this time we are not aware of any publications based on this data. If you have a publication you'd like to add please contact the TCIA Helpdesk.

Version 1 (Current): Updated 2017/10/25

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