Summary
ACRIN 6688, a [18F]-fluorothymidine (FLT) imaging study using positron emission tomography (PET), was designed to evaluate the relationship between [18F] FLT uptake parameters and pathologic complete response to neoadjuvant therapy of the primary tumor in patients with locally advanced breast cancer. Participant Eligibility and Enrollment: Criteria for inclusion were patients with pathologically confirmed breast cancer and determined to be a candidate for primary systemic (neoadjuvant) therapy and for whom surgical resection of residual primary tumor following completion of neoadjuvant therapy is planned. The study was open to enrollment from September 2009 to September 2012. Final accrual to the study was 90 patients, of which 80 were included in the analysis. Acknowledgements This shared data set was provided by Paul R. Jolles, MD, and David Mankoff, MD, PhD, and Lale Kostakoglu, MD, MPH, in collaboration with the American College of Radiology Imaging network (ACRIN). Many thanks are due to the ACRIN 6688 trial team, and all the patients participating in the study. This study was supported by ACRIN, which received funding from the National Cancer Institute through UO1 CA080098, under the American Recovery and Reinvestment ACT of 2009 (ARRA) and UO1 CA079778.
Data Access
Choosing the Download option will provide you with a file to launch the TCIA Download Manager to download the entire collection. If you want to browse or filter the data to select only specific scans/studies please use the Search By Collection option.
Click the Versions tab for more info about data releases.
Detailed Description
Collection Statistics |
|
---|---|
Modalities | |
Number of Patients | |
Number of Studies | |
Number of Series | |
Number of Images | |
Image Size (GB) |
Metadata
Much more information about this data set can be found https://www.acrin.org/6688_protocol.aspx
Citations & Data Usage Policy
This collection is freely available to browse, download, and use for commercial, scientific and educational purposes as outlined in the Creative Commons Attribution 3.0 Unported License. See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to help@cancerimagingarchive.net.
Please be sure to include the following citations in your work if you use this data set:
Data Citation
(authors list coming soon). (2017). Data from ACRIN-FLT-Breast. The Cancer Imaging Archive. http://doi.org//
TCIA Citation
Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. (paper)
Other Publications Using This Data
TCIA maintains a list of publications which leverage our data. At this time we are not aware of any publications based on this data. If you have a publication you'd like to add please contact the TCIA Helpdesk.