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Summary
Primary Aim Findings:[18F]fluorodeoxyglucose-PET/CT has high NPV for the N0 neck in T2 to T4 HNSCC. The surgical treatment plans on the basis of PET/CT findings may be changed in approximately 22% of this group. These findings suggest that [18F]fluorodeoxyglucose-PET/CT may assist the clinician in deciding on the best therapy for the clinically N0 neck in HNSCC. Well-designed clinical trials should be performed to test the outcome of omitting neck dissection by using PET/CT.
Study Design Summary: People with newly diagnosed head and neck squamous cell carcinoma being considered for surgical resection, with at least one side of the neck planned for dissection clinically N0, and at risk for occult metastasis (when risk based on clinical data is felt to be greater than 30%). A total of 287 participants were prospectively enrolled from 23 American College of Radiology Imaging Network-qualified institutions. PET/CT was compared with findings at neck dissection.
Acknowledgements
This shared data set was provided in collaboration with the American College of Radiology. Many thanks are due to the ACRIN 6685 trial team, and all the patients participating in the study.
Please see QIN ECOG-ACRIN Data Sharing page for an overview and list of other ECOG-ACRIN data collections available on TCIA.
Data Access
This is a limited access data set and is only available to members of NCI's Quantitative Imaging Network (QIN) with an anticipated public release of 2/XX/2021. If you are a member of the QIN and would like to request access, please submit a CCP proposal to the QIN Coordinating Committee. Once access is granted, click the Download button to save a ".tcia" manifest file to your computer, which you must open with the NBIA Data Retriever. Click the Search button to open our Data Portal, where you can browse the data collection and/or download a subset of its contents.
Data Type | Download all or Query/Filter |
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Images (DICOM, XX.X GB) |
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Clinical Data (XLS, zip) |
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- Click the Versions tab for more info about data releases.
Detailed Description
Image Statistics | |
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Modalities | CT, PT, MR, NM |
Number of Patients | 260 |
Number of Studies | 681 |
Number of Series | 3359* |
Number of Images | 460,983* |
Images Size (GB) | * |
- Estimated, official numbers provided once data is available.
Citations & Data Usage Policy
This is a limited access data set and is only available to members of NCI's Quantitative Imaging Network (QIN) until XX/XX/XXXX. If you are a member of the QIN and would like to request access, please submit a CCP proposal to the QIN Coordinating Committee. Upon receiving access you may only use it for the purposes outlined in your proposal. You are not allowed to redistribute the data or use it for other purposes. See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to help@cancerimagingarchive.net.
Please be sure to include the following citations in your work if you use this data set:
Data Citation
Kinahan, P., Muzi, M., Bialecki, B., & Coombs, L. (2019) DOI goes here.
Publication Citation
Lowe VJ, Duan F, Subramaniam RM, et al. Multicenter Trial of [18F]fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Staging of Head and Neck Cancer and Negative Predictive Value and Surgical Impact in the N0 Neck: Results From ACRIN 6685. J Clin Oncol. 2019 Feb 15. DOI: 10.1200/JCO.18.01182.
TCIA Citation
Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. DOI: 10.1007/s10278-013-9622-7
Other Publications Using This Data
TCIA maintains a list of publications which leverage TCIA data. If you have a manuscript you'd like to add please contact the TCIA Helpdesk.
Version 1 (Current): Updated 2020/mm/dd
Data Type | Download all or Query/Filter |
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Images (DICOM, xx.x GB) | (Requires NBIA Data Retriever.) |
Clinical Data (XLS, zip) |
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