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  • The Cancer Genome Atlas Breast Invasive Carcinoma Collection (TCGA-BRCA)

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Summary

The TCGA-BRCA data collection is part of a larger effort to enhance the The Cancer Genome Atlas (TCGA) data set with characterized radiological images.  The Cancer Imaging Program (CIP) with the cooperation of several of the TCGA tissue-contributing institutions are working to archive a large portion of the radiological images of the genetically-analyzed breast cancer cases.

Clinical, genetic, and pathology data resides in the TCGA data portal while the radiological data is stored on The Cancer Imaging Archive (TCIA).   The data utilizes the same TCGA patient identifiers in both repositories, allowing researchers to explore the correlations between tissue genotype and radiological phenotype. This Collection within TCIA is related to the BRCA disease type within TCGA.

We would like to acknowledge the individuals and institutions that have provided data for this collection:

  • Mayo Clinic, Rochester, MN - Special thanks to Bradley J. Erickson, MD, PhD from the Department of Radiology, Mayo Medical School.
  • Roswell Park Cancer Institute, Buffalo, NY - Special thanks to Ermelinda Bonaccio, MD and Joe Filippini from the Department of Diagnostic Radiology.
  • Memorial Sloan-Kettering Cancer Center, New York, NY - Special thanks to Elizabeth A Morris MD, Gloria Guman Figler, and Pierre Elnajjar
  • University of Pittsburgh/UPMC, Pittsburgh, PA - Special thanks to Margarita L Zuley MD, and Rose Jarosz.

CIP TCGA Radiology Initiative

The Cancer Imaging Program has begun multiple projects to collaborate with the academic community to encourage cross disciplinary research which utilizes the data provided in these resources.  Much more can be learned about this effort on the TCGA Breast Phenotype Research Group page.

Data Access

Imaging Data

You can view and download these images on The Cancer Imaging Archive by logging in to TCIA and selecting the TCGA-BRCA collection. A full listing of the available imaging studies/series for each patient can be found in this spreadsheet:TCGA-BRCA_series_descriptions.csv

Collection Statistics

Updated 12/20/2012

Modalities

MR, MG

Number of Patients

109 

Number of Studies

134

Number of Series

1,375

Number of Images

135,766

If you are unsure how to download this Collection please view our quick guide on Searching by Collection or refer to our The Cancer Imaging Archive User's Guide for more detailed instructions on using the site.

Metadata

The TCGA data portal has extensive clinical and genomic data which can be matched to the patient identifiers of the images here in TCIA.  Here are just a sample of some of the clinical data types available:

bcr_patient_barcode,age_at_initial_pathologic_diagnosis,days_to_birth,days_to_death,days_to_form_completion,days_to_initial_pathologic_diagnosis,
days_to_last_followup,days_to_last_known_alive,distant_metastasis_pathologic_spread,drugs,eastern_cancer_oncology_group,erythrocyte_sedimentation_rate_result,
gender,hemoglobin_result,histological_type,informed_consent_verified,karnofsky_performance_score,lactate_dehydrogenase_result,laterality,
lymphnode_pathologic_spread,lymphnodes_examined_prior_presentation,number_of_lymphnodes_examined,number_of_lymphnodes_positive,performance_status_scale_timing,
person_neoplasm_cancer_status,platelet_qualitative_result,pretreatment_history,primary_tumor_pathologic_spread,prior_diagnosis,radiations,serum_calcium_result,
tumor_grade,tumor_stage,tumor_tissue_site,vital_status,white_cell_count_result,year_of_initial_pathologic_diagnosis

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