Summary
This collection contains data from the National Cancer Institute Clinical Trial NCT00946712, "Carboplatin and Paclitaxel With or Without Bevacizumab and/or Cetuximab in Treating Patients With Stage IV or Recurrent Non-Small Cell Lung Cancer". It was sponsored by NCI's Alliance for Clinical Trials in Oncology under study number S0819. This randomized phase III trial studies carboplatin and paclitaxel to compare how well they work with or without bevacizumab and/or cetuximab in treating patients with stage IV or non-small cell lung cancer that has returned after a period of improvement (recurrent). Drugs used in chemotherapy, such as carboplatin and paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Bevacizumab may prevent the growth of new blood vessels that tumor needs to grow. Cetuximab may also stop cancer cells from growing by binding and interfering with a protein on the surface of the tumor cell that is needed for tumor growth. It is not yet known whether giving carboplatin and paclitaxel are more effective with or without bevacizumab and/or cetuximab in treating patients with non-small cell lung cancer.Acknowledgements
We would like to acknowledge the individuals and institutions that have provided data for this collection:
Data Access
This is a limited access data set. To request access please register an account on the NCTN Data Archive and use the "Request Data" link in the left side menu. Follow the on screen instructions, and enter NCT00946712 when asked which trial you want to request. In step 2 of the Create Request form, be sure to select “Imaging Data Requested”. Please contact NCINCTNDataArchive@mail.nih.gov for any questions about access requests.
| Data Type | Download all or Query/Filter |
|---|---|
Images, Segmentations, and Radiation Therapy Structures/Doses/Plans (DICOM, XX.X GB) << latter two items only if DICOM SEG/RTSTRUCT/RTDOSE/PLAN exist >> | (Download requires the NBIA Data Retriever) |
| Tissue Slide Images (SVS, XX.X GB) | |
| Clinical data (CSV) |
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Detailed Description
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Number of Patients | 1299 |
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Citations & Data Usage Policy
This is a limited access data set. You are not allowed to redistribute the data or use it for other purposes. Requests from the NCTN/NCORP (how to request data?). See TCIA's Data Usage Policies and Restrictions for additional details. Questions may be directed to help@cancerimagingarchive.net.
Please be sure to acknowledge both this data set and TCIA in publications by including the following citations in your work:
Data Citation
Pending, DOI goes here.
Publication Citation
Pending
Acknowledgement
Only if they ask for special acknowledgments like funding sources, grant numbers, etc in their proposal.
TCIA Citation
Clark K, Vendt B, Smith K, Freymann J, Kirby J, Koppel P, Moore S, Phillips S, Maffitt D, Pringle M, Tarbox L, Prior F. The Cancer Imaging Archive (TCIA): Maintaining and Operating a Public Information Repository, Journal of Digital Imaging, Volume 26, Number 6, December, 2013, pp 1045-1057. DOI: 10.1007/s10278-013-9622-7
Other Publications Using This Data
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Version X (Current): Updated yyyy/mm/dd
| Data Type | Download all or Query/Filter |
|---|---|
| Images (DICOM, xx.x GB) | (Requires NBIA Data Retriever.) |
| Clinical Data (CSV) | Link |
| Other (format) |
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