The Cancer Imaging Archive (TCIA) Public Access

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The NCI Cancer Imaging Program is offering those few specific cases, access-linked here-in, as an opportunity for researchers to explore and comprehend what such combined research resources might offer. They consist of 12 ovarian (TCGA-OV) and 7 breast (TCGA-BRCA) cases. Those imaging cases are easily downloadable as individual groups from TCIA by entering separate queries of “shared lists” entitled: CPTAC BreastAnalyzed (7 breast cases), and CPTAC OV Analyzed (12 ovarian cases). Those image cases can be down-loaded by entering the afore-mentioned “shared lists” on https://public.cancerimagingarchive.net/ncia/searchCustomList.jsf  Their match-able CPTAC proteomic analysis data is down-loadable from: https://cptac-data-portal.georgetown.edu/cptacPublic/  The case specific clinical data matching each of those TCIA stored image cases are attached here as XLS sheets.

An early CPTAC publication which reports on a more comprehensive collection of cases from those TCGA tumor data collections (BRCA and OV) can be found at: “Comprehensive quantitative analysis of ovarian and breast cancer tumor peptidomes”. Xu Z, et al., J Proteome Res. 2015 Jan 2;14(1):422-33. doi: 10.1021/pr500840w. 

CPTAC and TCGA Collections Publication Guidelines

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The specific status of each tumor data set is available on the Data Usage Policies and Restrictions page. Do not hesitate to contact help@cancerimagingarchive.net with any questions.

 

Ongoing Research Efforts

CIP continues to encourage ad hoc multi-institutional research teams to analyze these data sets as they are collected. Efforts have begun or are being initiated for the following TCGA tissue types.  Points of contact for collaborating with the existing research groups can be found on their respective pages.

 

Group Name

Tumor Type

TCGA Breast Phenotype Research Group

Breast invasive carcinoma (BRCA)

TCGA Glioma Phenotype Research Group

Glioblastoma (GBM), lower grade glioma (LGG)

TCGA Head-Neck Phenotype Research Group

Head-neck squamous cell carcinoma (HNSC)

TCGA Renal Phenotype Research Group

Kidney renal clear cell carcinoma (KIRC)

TCGA Ovarian Phenotype Research Group

Ovarian serous cystadenocarcinoma (OV) 

 

References

The following links contain publications from the main TCGA project as well as their posted publication guidelines:

Included below are some posters and presentations which help summarize the CIP TCGA Radiology Initiative and its supporting components such as TCIA.

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Data Downloads

 

 

References

An early CPTAC publication which reports on a more comprehensive collection of cases from those TCGA tumor data collections (BRCA and OV) can be found at: “Comprehensive quantitative analysis of ovarian and breast cancer tumor peptidomes”. Xu Z, et al., J Proteome Res. 2015 Jan 2;14(1):422-33. doi: 10.1021/pr500840w.