Versions Compared
Key
- This line was added.
- This line was removed.
- Formatting was changed.
Summary
Excerpt |
---|
Finding better therapies for the treatment of brain tumors is hampered by the lack of consistently obtained molecular data in a large sample set and the ability to integrate biomedical data from disparate sources enabling translation of therapies from bench to bedside. Hence, a critical factor in the advancement of biomedical research and clinical translation is the ease with which data can be integrated, redistributed, and analyzed both within and across functional domains. Novel biomedical informatics infrastructure and tools are essential for developing individualized patient treatment based on the specific genomic signatures in each patient's tumor. The Repository of Molecular Brain Neoplasia Data (REMBRANDT) is aimed at facilitating discovery by connecting the dots between clinical information and genomic characterization data. |
Rembrandt contains data generated through the Glioma Molecular Diagnostic Initiative from 874 glioma specimens comprising approximately 566 gene expression arrays, 834 copy number arrays, and 13,472 clinical phenotype data points. These data are currently housed in Georgetown University's G-DOC System and are described in a related manuscript. This image collection was created as a companion data set to augment the
larger REMBRANDT project. It consists of 130 cases of magnecticlarger REMBRANDT project. It contains the pre-surgical magnetic resonance (MR) multi-sequence images
of pre-surgical brain tumor patients; including cases of glioblastoma, astrocytomas, and oligodendrogliomas from the REMBRANDT patient population.from 130 REMBRANDT patients.
For scientific inquiries about the VASARI feature set or corresponding analysis, please contact Adam Flanders at adam.flanders@jefferson.edu.
Localtab Group | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|