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Presently, CIP is developing agreements with many of the TCGA Tissue Site Source institutions to recover and place in the Image Archive collections of diagnostic images that match the genomic data now being deposited in the publically accessible TCGA Data Portal on cancers of the brain (GBM/LGG), breast (BRCA), renal (KIRC), lung (LUAD), and in due time, many of the future 20-plus tumors that TCGA will characterize as the program moves forward. Imaging Source Site (ISS) Groups are being created and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, these groups are given the opportunity to publish a marker paper for a given cancer type per the aforementioned publication policy. It is hoped that this will generate increased participation in the building of these multi-institutional data sets that become an open community resource.
Publication Policies
TCIA publication guidelines are derived from the policy outlined by the The Cancer Genome Atlas. These must be followed in addition to the publication policy of the TCGA Data Portal: http://cancergenome.nih.gov/abouttcga/policies/publicationguidelines.
There are no limitations on publications containing analyses using any TCGA-linked imaging data set if the data set meets one of the following three freedom-to-publish criteria:
- A marker paper has been published on that tumor type; or
- 12 months after 100 cases of a given tumor type have had their DICOM data published on TCIA; or
- The author receives specific approval from the TCGA Image Source Site (ISS) Groups representing any relevant tumor types.
Imaging Source Site (ISS) Groups will be populated and governed by participants from institutions that have provided imaging data to the archive for a given cancer type. Modeled after TCGA analysis groups, these groups are given the opportunity to publish a marker paper for a given cancer type per the aforementioned publication policy. It is hoped that this will generate increased participation in the building of these multi-institutional data sets that become an open community resource.
Specifically, the status of each tumor data set is available below. If you have questions, do not hesitate to contact cancerimagingarchive@mail.nih.gov.
Tumor Type | Data Status |
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No restrictions; image data available without limitations | |
Publication limitations in place until 08/22/2013 | |
Publication limitations in place until 10/16/2013 | |
Projects have not reached 100 imaging cases; Please check with cancerimagingarchive@mail.nih.gov prior to any publication |
Ongoing Research Efforts
Continuing these efforts CIP is working to enable ad hoc multi-institutional research teams for analysis of these data sets as they are collected. Efforts have already begun or are being initiated for the following TCGA tissue types:
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Group Name | Tumor Type | Status |
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Open | ||
ISS only | ||
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ISS only | ||
ISS only | ||
TCGA-LGG Phenotype Research Group | ISS only | |
TCGA-PRAD Phenotype Research Group | Prostate adenocarcinoma (PRAD) | ISS only |
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Please contact us at cancerimagingarchive@mail.nih.gov if you would like to
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join our public mailing lists to receive notifications of newly available data and other news items related to these data sets.
References
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Included below are some posters and presentations which help summarize the CIP TCGA Radiology Initiative and its supporting components such as TCIA.
- Imaging and Genomics: Is There a Synergy? - Published in August 2012 Radiology, 264, 329-331.
- A Scalable Methodology for Correlating Clinical Imaging Features with TCGA Data - Presented at TCGA Network Symposium, November 17-18, Washington, DC
- The Cancer Imaging Archive: a Repository of Advanced Imaging Information Correlated with TCGA Samples - Presented at TCGA Network Symposium, November 17-18, Washington, DC
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The following links contain publications from the main TCGA project, as well as their posted publication guidelines.
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